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Leveraging global gene expression patterns to predict expression of unmeasured genes

BACKGROUND: Large collections of paraffin-embedded tissue represent a rich resource to test hypotheses based on gene expression patterns; however, measurement of genome-wide expression is cost-prohibitive on a large scale. Using the known expression correlation structure within a given disease type...

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Detalles Bibliográficos
Autores principales: Rudd, James, Zelaya, René A., Demidenko, Eugene, Goode, Ellen L., Greene, Casey S., Doherty, Jennifer A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4678722/
https://www.ncbi.nlm.nih.gov/pubmed/26666289
http://dx.doi.org/10.1186/s12864-015-2250-5