A continuous kinetic assay for protein and DNA methyltransferase enzymatic activities

BACKGROUND: Methyltransferases (MTs) catalyze the S-adenosylmethionine (SAM)-dependent methylation of a wide variety of protein and DNA substrates. Methylation of lysine, arginine or cytosine regulates a variety of biological processes including transcriptional activation and gene silencing. Despite...

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Detalles Bibliográficos
Autores principales: Duchin, Shai, Vershinin, Zlata, Levy, Dan, Aharoni, Amir
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Methodology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4678762/
https://www.ncbi.nlm.nih.gov/pubmed/26675044
http://dx.doi.org/10.1186/s13072-015-0048-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4678762/
https://www.ncbi.nlm.nih.gov/pubmed/26675044
http://dx.doi.org/10.1186/s13072-015-0048-y

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