Effects of pyrrolidine dithiocarbamate on proliferation and nuclear factor-κB activity in autosomal dominant polycystic kidney disease cells

BACKGROUND: Pyrrolidine dithiocarbamate (PDTC) reduces renal cyst growth in a rodent model of polycystic kidney disease (PKD) but the mechanism of action is not clear. Here, we investigated the hypothesis that PDTC reduces the proliferation of cystic epithelial cells in vitro in a nuclear factor (NF...

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Detalles Bibliográficos
Autores principales: Ta, Michelle H. T., Liuwantara, David, Rangan, Gopala K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4678764/
https://www.ncbi.nlm.nih.gov/pubmed/26666710
http://dx.doi.org/10.1186/s12882-015-0193-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4678764/
https://www.ncbi.nlm.nih.gov/pubmed/26666710
http://dx.doi.org/10.1186/s12882-015-0193-3

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