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Allosteric ring assembly and chemo-mechanical melting by the interaction between 5′-phosphate and λ exonuclease
Phosphates along the DNA function as chemical energy frequently used by nucleases to drive their enzymatic reactions. Exonuclease functions as a machine that converts chemical energy of the phosphodiester-chain into mechanical work. However, the roles of phosphates during exonuclease activities are...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Oxford University Press
2015
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4678818/ https://www.ncbi.nlm.nih.gov/pubmed/26527731 http://dx.doi.org/10.1093/nar/gkv1150 |