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Re-evaluating the kinetics of ATP hydrolysis during initiation of DNA sliding by Type III restriction enzymes

DNA cleavage by the Type III restriction enzymes requires long-range protein communication between recognition sites facilitated by thermally-driven 1D diffusion. This ‘DNA sliding’ is initiated by hydrolysis of multiple ATPs catalysed by a helicase-like domain. Two distinct ATPase phases were obser...

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Detalles Bibliográficos
Autores principales: Tóth, Júlia, Bollins, Jack, Szczelkun, Mark D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4678819/
https://www.ncbi.nlm.nih.gov/pubmed/26538601
http://dx.doi.org/10.1093/nar/gkv1154