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GEN1 promotes Holliday junction resolution by a coordinated nick and counter-nick mechanism

Holliday junctions (HJs) that physically link sister chromatids or homologous chromosomes are formed as intermediates during DNA repair by homologous recombination. Persistent recombination intermediates are acted upon by structure-selective endonucleases that are required for proper chromosome segr...

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Detalles Bibliográficos
Autores principales: Chan, Ying Wai, West, Stephen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4678824/
https://www.ncbi.nlm.nih.gov/pubmed/26578604
http://dx.doi.org/10.1093/nar/gkv1207