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GEN1 promotes Holliday junction resolution by a coordinated nick and counter-nick mechanism
Holliday junctions (HJs) that physically link sister chromatids or homologous chromosomes are formed as intermediates during DNA repair by homologous recombination. Persistent recombination intermediates are acted upon by structure-selective endonucleases that are required for proper chromosome segr...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4678824/ https://www.ncbi.nlm.nih.gov/pubmed/26578604 http://dx.doi.org/10.1093/nar/gkv1207 |