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Structural basis for RNA-genome recognition during bacteriophage Qβ replication

Upon infection of Escherichia coli by bacteriophage Qβ, the virus-encoded β-subunit recruits host translation elongation factors EF-Tu and EF-Ts and ribosomal protein S1 to form the Qβ replicase holoenzyme complex, which is responsible for amplifying the Qβ (+)-RNA genome. Here, we use X-ray crystal...

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Detalles Bibliográficos
Autores principales: Gytz, Heidi, Mohr, Durita, Seweryn, Paulina, Yoshimura, Yuichi, Kutlubaeva, Zarina, Dolman, Fleur, Chelchessa, Bosene, Chetverin, Alexander B., Mulder, Frans A. A., Brodersen, Ditlev E., Knudsen, Charlotte R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4678825/
https://www.ncbi.nlm.nih.gov/pubmed/26578560
http://dx.doi.org/10.1093/nar/gkv1212