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Probing the active site tryptophan of Staphylococcus aureus thioredoxin with an analog

Genetically encoded non-canonical amino acids are powerful tools of protein research and engineering; in particular they allow substitution of individual chemical groups or atoms in a protein of interest. One such amino acid is the tryptophan (Trp) analog 3-benzothienyl-l-alanine (Bta) with an imino...

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Detalles Bibliográficos
Autores principales: Englert, Markus, Nakamura, Akiyoshi, Wang, Yane-Shih, Eiler, Daniel, Söll, Dieter, Guo, Li-Tao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4678829/
https://www.ncbi.nlm.nih.gov/pubmed/26582921
http://dx.doi.org/10.1093/nar/gkv1255