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The structures of the SNM1A and SNM1B/Apollo nuclease domains reveal a potential basis for their distinct DNA processing activities

The human SNM1A and SNM1B/Apollo proteins are members of an extended family of eukaryotic nuclease containing a motif related to the prokaryotic metallo-β-lactamase (MBL) fold. SNM1A is a key exonuclease during replication-dependent and transcription-coupled interstrand crosslink repair, while SNM1B...

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Detalles Bibliográficos
Autores principales: Allerston, Charles K., Lee, Sook Y., Newman, Joseph A., Schofield, Christopher J., McHugh, Peter J., Gileadi, Opher
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4678830/
https://www.ncbi.nlm.nih.gov/pubmed/26582912
http://dx.doi.org/10.1093/nar/gkv1256