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The structures of the SNM1A and SNM1B/Apollo nuclease domains reveal a potential basis for their distinct DNA processing activities
The human SNM1A and SNM1B/Apollo proteins are members of an extended family of eukaryotic nuclease containing a motif related to the prokaryotic metallo-β-lactamase (MBL) fold. SNM1A is a key exonuclease during replication-dependent and transcription-coupled interstrand crosslink repair, while SNM1B...
Autores principales: | Allerston, Charles K., Lee, Sook Y., Newman, Joseph A., Schofield, Christopher J., McHugh, Peter J., Gileadi, Opher |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4678830/ https://www.ncbi.nlm.nih.gov/pubmed/26582912 http://dx.doi.org/10.1093/nar/gkv1256 |
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