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Comparative genomic analyses reveal a vast, novel network of nucleotide-centric systems in biological conflicts, immunity and signaling

Cyclic di- and linear oligo-nucleotide signals activate defenses against invasive nucleic acids in animal immunity; however, their evolutionary antecedents are poorly understood. Using comparative genomics, sequence and structure analysis, we uncovered a vast network of systems defined by conserved...

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Detalles Bibliográficos
Autores principales: Burroughs, A. Maxwell, Zhang, Dapeng, Schäffer, Daniel E., Iyer, Lakshminarayan M., Aravind, L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4678834/
https://www.ncbi.nlm.nih.gov/pubmed/26590262
http://dx.doi.org/10.1093/nar/gkv1267