Cargando…
Comparative genomic analyses reveal a vast, novel network of nucleotide-centric systems in biological conflicts, immunity and signaling
Cyclic di- and linear oligo-nucleotide signals activate defenses against invasive nucleic acids in animal immunity; however, their evolutionary antecedents are poorly understood. Using comparative genomics, sequence and structure analysis, we uncovered a vast network of systems defined by conserved...
Autores principales: | Burroughs, A. Maxwell, Zhang, Dapeng, Schäffer, Daniel E., Iyer, Lakshminarayan M., Aravind, L. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2015
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4678834/ https://www.ncbi.nlm.nih.gov/pubmed/26590262 http://dx.doi.org/10.1093/nar/gkv1267 |
Ejemplares similares
-
Computational identification of novel biochemical systems involved in oxidation, glycosylation and other complex modifications of bases in DNA
por: Iyer, Lakshminarayan M., et al.
Publicado: (2013) -
Transposons to toxins: the provenance, architecture and diversification of a widespread class of eukaryotic effectors
por: Zhang, Dapeng, et al.
Publicado: (2016) -
Jumbo Phages: A Comparative Genomic Overview of Core Functions and Adaptions for Biological Conflicts
por: M. Iyer, Lakshminarayan, et al.
Publicado: (2021) -
Highly regulated, diversifying NTP-dependent biological conflict systems with implications for the emergence of multicellularity
por: Kaur, Gurmeet, et al.
Publicado: (2020) -
Bacterial death and TRADD-N domains help define novel apoptosis and immunity mechanisms shared by prokaryotes and metazoans
por: Kaur, Gurmeet, et al.
Publicado: (2021)