Oligonucleotide gap-fill ligation for mutation detection and sequencing in situ

In clinical diagnostics a great need exists for targeted in situ multiplex nucleic acid analysis as the mutational status can offer guidance for effective treatment. One well-established method uses padlock probes for mutation detection and multiplex expression analysis directly in cells and tissues...

Descripción completa

Detalles Bibliográficos
Autores principales: Mignardi, Marco, Mezger, Anja, Qian, Xiaoyan, La Fleur, Linnea, Botling, Johan, Larsson, Chatarina, Nilsson, Mats
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2015
Materias:
Methods Online
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4678841/
https://www.ncbi.nlm.nih.gov/pubmed/26240388
http://dx.doi.org/10.1093/nar/gkv772

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4678841/
https://www.ncbi.nlm.nih.gov/pubmed/26240388
http://dx.doi.org/10.1093/nar/gkv772

Ejemplares similares