Effects of non-CpG site methylation on DNA thermal stability: a fluorescence study

Cytosine methylation is a widespread epigenetic regulation mechanism. In healthy mature cells, methylation occurs at CpG dinucleotides within promoters, where it primarily silences gene expression by modifying the binding affinity of transcription factors to the promoters. Conversely, a recent study...

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Detalles Bibliográficos
Autores principales: Nardo, Luca, Lamperti, Marco, Salerno, Domenico, Cassina, Valeria, Missana, Natalia, Bondani, Maria, Tempestini, Alessia, Mantegazza, Francesco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2015
Materias:
Gene regulation, Chromatin and Epigenetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4678853/
https://www.ncbi.nlm.nih.gov/pubmed/26354864
http://dx.doi.org/10.1093/nar/gkv884

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4678853/
https://www.ncbi.nlm.nih.gov/pubmed/26354864
http://dx.doi.org/10.1093/nar/gkv884

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