Conformational toggling controls target site choice for the heteromeric transposase element Tn7

The bacterial transposon Tn7 facilitates horizontal transfer by directing transposition into actively replicating DNA with the element-encoded protein TnsE. Structural analysis of the C-terminal domain of wild-type TnsE identified a novel protein fold including a central V-shaped loop that toggles b...

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Detalles Bibliográficos
Autores principales: Shi, Qiaojuan, Straus, Marco R., Caron, Jeremy J., Wang, Huasheng, Chung, Yu Seon, Guarné, Alba, Peters, Joseph E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2015
Materias:
Genome Integrity, Repair and Replication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4678854/
https://www.ncbi.nlm.nih.gov/pubmed/26384427
http://dx.doi.org/10.1093/nar/gkv913

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4678854/
https://www.ncbi.nlm.nih.gov/pubmed/26384427
http://dx.doi.org/10.1093/nar/gkv913

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