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The PIN domain of EXO1 recognizes poly(ADP-ribose) in DNA damage response

Following DNA double-strand breaks, poly(ADP-ribose) (PAR) is quickly and heavily synthesized to mediate fast and early recruitment of a number of DNA damage response factors to the sites of DNA lesions and facilitates DNA damage repair. Here, we found that EXO1, an exonuclease for DNA damage repair...

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Detalles Bibliográficos
Autores principales: Zhang, Feng, Shi, Jiazhong, Chen, Shih-Hsun, Bian, Chunjing, Yu, Xiaochun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4678857/
https://www.ncbi.nlm.nih.gov/pubmed/26400172
http://dx.doi.org/10.1093/nar/gkv939