Cargando…
The PIN domain of EXO1 recognizes poly(ADP-ribose) in DNA damage response
Following DNA double-strand breaks, poly(ADP-ribose) (PAR) is quickly and heavily synthesized to mediate fast and early recruitment of a number of DNA damage response factors to the sites of DNA lesions and facilitates DNA damage repair. Here, we found that EXO1, an exonuclease for DNA damage repair...
Autores principales: | Zhang, Feng, Shi, Jiazhong, Chen, Shih-Hsun, Bian, Chunjing, Yu, Xiaochun |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2015
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4678857/ https://www.ncbi.nlm.nih.gov/pubmed/26400172 http://dx.doi.org/10.1093/nar/gkv939 |
Ejemplares similares
-
The WD40 domain of FBXW7 is a poly(ADP-ribose)-binding domain that mediates the early DNA damage response
por: Zhang, Qiang, et al.
Publicado: (2019) -
PARG is recruited to DNA damage sites through poly(ADP-ribose)- and PCNA-dependent mechanisms
por: Mortusewicz, Oliver, et al.
Publicado: (2011) -
Quantitative proteomics profiling of the poly(ADP-ribose)-related response to genotoxic stress
por: Gagné, Jean-Philippe, et al.
Publicado: (2012) -
Poly(ADP-ribose)-dependent chromatin unfolding facilitates the association of DNA-binding proteins with DNA at sites of damage
por: Smith, Rebecca, et al.
Publicado: (2019) -
Poly(ADP-ribose) polymerases covalently modify strand break termini in DNA fragments in vitro
por: Talhaoui, Ibtissam, et al.
Publicado: (2016)