Acid-sensing ion channel (ASIC) 4 predominantly localizes to an early endosome-related organelle upon heterologous expression

Acid-sensing ion channels (ASICs) are voltage-independent proton-gated amiloride sensitive sodium channels, belonging to the DEG/ENaC gene family. Six different ASICs have been identified (ASIC1a, ASIC1b, ASIC2a, ASIC2b, ASIC3, ASIC4) that are activated by a drop in extracellular pH, either as homo-...

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Detalles Bibliográficos
Autores principales: Schwartz, Verena, Friedrich, Katharina, Polleichtner, Georg, Gründer, Stefan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4678866/
https://www.ncbi.nlm.nih.gov/pubmed/26667795
http://dx.doi.org/10.1038/srep18242

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4678866/
https://www.ncbi.nlm.nih.gov/pubmed/26667795
http://dx.doi.org/10.1038/srep18242

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