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Two domain-disrupted hda6 alleles have opposite epigenetic effects on transgenes and some endogenous targets

HDA6 is a RPD3-like histone deacetylase. In Arabidopsis, it mediates transgene and some endogenous target transcriptional gene silencing (TGS) via histone deacetylation and DNA methylation. Here, we characterized two hda6 mutant alleles that were recovered as second-site suppressors of the DNA demet...

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Detalles Bibliográficos
Autores principales: Zhang, Shoudong, Zhan, Xiangqiang, Xu, Xiaoming, Cui, Peng, Zhu, Jian-Kang, Xia, Yiji, Xiong, Liming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4678874/
https://www.ncbi.nlm.nih.gov/pubmed/26666962
http://dx.doi.org/10.1038/srep17832