Reverse Electron Transfer Completes the Catalytic Cycle in a 2,3,5-Trifluorotyrosine-Substituted Ribonucleotide Reductase

[Image: see text] Escherichia coli class Ia ribonucleotide reductase is composed of two subunits (α and β), which form an α2β2 complex that catalyzes the conversion of nucleoside 5′-diphosphates to deoxynucleotides (dNDPs). β2 contains the essential tyrosyl radical (Y(122)(•)) that generates a thiyl...

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Detalles Bibliográficos
Autores principales: Ravichandran, Kanchana R., Minnihan, Ellen C., Wei, Yifeng, Nocera, Daniel G., Stubbe, JoAnne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2015
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4678968/
https://www.ncbi.nlm.nih.gov/pubmed/26492582
http://dx.doi.org/10.1021/jacs.5b09189

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4678968/
https://www.ncbi.nlm.nih.gov/pubmed/26492582
http://dx.doi.org/10.1021/jacs.5b09189

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