Suppression of AGO2 by miR-132 as a determinant of miRNA-mediated silencing in human primary endothelial cells

The abundance of miR-132 ranges from constitutively high in the brain where it is necessary for neuronal development and function, to inducible expression in haematopoietic and endothelial cells where it controls angiogenesis and immune activation. We show that expression of AGO2, a protein central...

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Detalles Bibliográficos
Autores principales: Leonov, German, Shah, Kunal, Yee, Daniel, Timmis, Jon, Sharp, Tyson V., Lagos, Dimitris
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4679077/
https://www.ncbi.nlm.nih.gov/pubmed/26475020
http://dx.doi.org/10.1016/j.biocel.2015.10.006

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4679077/
https://www.ncbi.nlm.nih.gov/pubmed/26475020
http://dx.doi.org/10.1016/j.biocel.2015.10.006

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