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Suppression of AGO2 by miR-132 as a determinant of miRNA-mediated silencing in human primary endothelial cells
The abundance of miR-132 ranges from constitutively high in the brain where it is necessary for neuronal development and function, to inducible expression in haematopoietic and endothelial cells where it controls angiogenesis and immune activation. We show that expression of AGO2, a protein central...
Autores principales: | Leonov, German, Shah, Kunal, Yee, Daniel, Timmis, Jon, Sharp, Tyson V., Lagos, Dimitris |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4679077/ https://www.ncbi.nlm.nih.gov/pubmed/26475020 http://dx.doi.org/10.1016/j.biocel.2015.10.006 |
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