Feasibility of Affibody Molecule-Based PNA-Mediated Radionuclide Pretargeting of Malignant Tumors

Affibody molecules are small (7 kDa), non-immunoglobulin scaffold proteins with a potential as targeting agents for radionuclide imaging of cancer. However, high renal re-absorption of Affibody molecules prevents their use for radionuclide therapy with residualizing radiometals. We hypothesized that...

Descripción completa

Detalles Bibliográficos
Autores principales: Honarvar, Hadis, Westerlund, Kristina, Altai, Mohamed, Sandström, Mattias, Orlova, Anna, Tolmachev, Vladimir, Karlström, Amelie Eriksson
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4679357/
https://www.ncbi.nlm.nih.gov/pubmed/26722376
http://dx.doi.org/10.7150/thno.12766

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4679357/
https://www.ncbi.nlm.nih.gov/pubmed/26722376
http://dx.doi.org/10.7150/thno.12766

Ejemplares similares