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Feasibility of Affibody Molecule-Based PNA-Mediated Radionuclide Pretargeting of Malignant Tumors
Affibody molecules are small (7 kDa), non-immunoglobulin scaffold proteins with a potential as targeting agents for radionuclide imaging of cancer. However, high renal re-absorption of Affibody molecules prevents their use for radionuclide therapy with residualizing radiometals. We hypothesized that...
Autores principales: | Honarvar, Hadis, Westerlund, Kristina, Altai, Mohamed, Sandström, Mattias, Orlova, Anna, Tolmachev, Vladimir, Karlström, Amelie Eriksson |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Ivyspring International Publisher
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4679357/ https://www.ncbi.nlm.nih.gov/pubmed/26722376 http://dx.doi.org/10.7150/thno.12766 |
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