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Reversine Increases the Plasticity of Long-Term Cryopreserved Fibroblasts to Multipotent Progenitor Cells through Activation of Oct4

Reversine, a purine analog, had been evidenced that it could induce dedifferentiation of differentiated cells into multipotent progenitor cells. Here, we showed that reversine could increase the plasticity of long-term cryopreserved bovine fibroblasts, and reversine-treated cells achieved the abilit...

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Detalles Bibliográficos
Autores principales: Li, Xiangchen, Guo, Yu, Yao, Yaxin, Hua, Jinlian, Ma, Yuehui, Liu, Changqing, Guan, Weijun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4679398/
https://www.ncbi.nlm.nih.gov/pubmed/26722217
http://dx.doi.org/10.7150/ijbs.12199