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Isovitexin Exerts Anti-Inflammatory and Anti-Oxidant Activities on Lipopolysaccharide-Induced Acute Lung Injury by Inhibiting MAPK and NF-κB and Activating HO-1/Nrf2 Pathways

Oxidative damage and inflammation are closely associated with the pathogenesis of acute lung injury (ALI). Thus, we explored the protective effect of isovitexin (IV), a glycosylflavonoid, in the context of ALI. To accomplish this, we created in vitro and in vivo models by respectively exposing macro...

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Detalles Bibliográficos
Autores principales: Lv, Hongming, Yu, Zhenxiang, Zheng, Yuwei, Wang, Lidong, Qin, Xiaofeng, Cheng, Genhong, Ci, Xinxin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4679400/
https://www.ncbi.nlm.nih.gov/pubmed/26722219
http://dx.doi.org/10.7150/ijbs.13188