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Genetic Regulation of Sinoatrial Node Development and Pacemaker Program in the Venous Pole
The definitive sinoatrial node (SAN), the primary pacemaker of the mammalian heart, develops from part of pro-pacemaking embryonic venous pole that expresses both Hcn4 and the transcriptional factor Shox2. It is noted that ectopic pacemaking activities originated from the myocardial sleeves of the p...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4679406/ https://www.ncbi.nlm.nih.gov/pubmed/26682210 http://dx.doi.org/10.3390/jcdd2040282 |