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Genetic Regulation of Sinoatrial Node Development and Pacemaker Program in the Venous Pole

The definitive sinoatrial node (SAN), the primary pacemaker of the mammalian heart, develops from part of pro-pacemaking embryonic venous pole that expresses both Hcn4 and the transcriptional factor Shox2. It is noted that ectopic pacemaking activities originated from the myocardial sleeves of the p...

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Detalles Bibliográficos
Autores principales: Ye, Wenduo, Song, Yingnan, Huang, Zhen, Zhang, Yanding, Chen, Yiping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4679406/
https://www.ncbi.nlm.nih.gov/pubmed/26682210
http://dx.doi.org/10.3390/jcdd2040282