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Circadian rhythm influences genome-wide transcriptional responses to (131)I in a tissue-specific manner in mice

BACKGROUND: Circadian variation of gene expression is often neglected when ionizing radiation-induced effects are studied, whether in animal models or in cell culture. This study characterized diurnal variation of genome-wide transcriptional regulation and responses of potential biomarkers and signa...

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Detalles Bibliográficos
Autores principales: Langen, Britta, Rudqvist, Nils, Parris, Toshima Z., Helou, Khalil, Forssell-Aronsson, Eva
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4679710/
https://www.ncbi.nlm.nih.gov/pubmed/26669694
http://dx.doi.org/10.1186/s13550-015-0150-y