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Ubiquitylation as a Rheostat for TCR Signaling: From Targeted Approaches Toward Global Profiling
T cell receptor (TCR) signaling must be precisely tuned to limit collateral damage and prevent reactivity to self, while still allowing robust protective immune responses that control pathogen invasion. One process that can be used to promote, modify, or terminate TCR signaling is ubiquitylation. Du...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Frontiers Media S.A.
2015
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4679856/ https://www.ncbi.nlm.nih.gov/pubmed/26732666 http://dx.doi.org/10.3389/fimmu.2015.00618 |