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Reduced Responses of Submucous Neurons from Irritable Bowel Syndrome Patients to a Cocktail Containing Histamine, Serotonin, TNFα, and Tryptase (IBS-Cocktail)

Background and Aims: Malfunctions of enteric neurons are believed to play an important role in the pathophysiology of irritable bowel syndrome (IBS). Our aim was to investigate whether neuronal activity in biopsies from IBS patients is altered in comparison to healthy controls (HC). Methods: Activit...

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Detalles Bibliográficos
Autores principales: Ostertag, Daniela, Buhner, Sabine, Michel, Klaus, Pehl, Christian, Kurjak, Manfred, Götzberger, Manuela, Schulte-Frohlinde, Ewert, Frieling, Thomas, Enck, Paul, Phillip, Josef, Schemann, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4679876/
https://www.ncbi.nlm.nih.gov/pubmed/26733780
http://dx.doi.org/10.3389/fnins.2015.00465