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Reduced Responses of Submucous Neurons from Irritable Bowel Syndrome Patients to a Cocktail Containing Histamine, Serotonin, TNFα, and Tryptase (IBS-Cocktail)
Background and Aims: Malfunctions of enteric neurons are believed to play an important role in the pathophysiology of irritable bowel syndrome (IBS). Our aim was to investigate whether neuronal activity in biopsies from IBS patients is altered in comparison to healthy controls (HC). Methods: Activit...
Autores principales: | Ostertag, Daniela, Buhner, Sabine, Michel, Klaus, Pehl, Christian, Kurjak, Manfred, Götzberger, Manuela, Schulte-Frohlinde, Ewert, Frieling, Thomas, Enck, Paul, Phillip, Josef, Schemann, Michael |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4679876/ https://www.ncbi.nlm.nih.gov/pubmed/26733780 http://dx.doi.org/10.3389/fnins.2015.00465 |
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