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Chronic Glutamate Toxicity in Neurodegenerative Diseases—What is the Evidence?
Together with aspartate, glutamate is the major excitatory neurotransmitter in the brain. Glutamate binds and activates both ligand-gated ion channels (ionotropic glutamate receptors) and a class of G-protein coupled receptors (metabotropic glutamate receptors). Although the intracellular glutamate...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Frontiers Media S.A.
2015
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4679930/ https://www.ncbi.nlm.nih.gov/pubmed/26733784 http://dx.doi.org/10.3389/fnins.2015.00469 |