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Integration of Mitochondrial Targeting for Molecular Cancer Therapeutics

Mitochondrial metabolism greatly influences cancer cell survival, invasion, metastasis, and resistance to many anticancer drugs. Furthermore, molecular-targeted therapies (e.g., oncogenic kinase inhibitors) create a dependence of surviving cells on mitochondrial metabolism. For these reasons, inhibi...

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Detalles Bibliográficos
Autores principales: Marchetti, Philippe, Guerreschi, Pierre, Mortier, Laurent, Kluza, Jerome
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4680051/
https://www.ncbi.nlm.nih.gov/pubmed/26713093
http://dx.doi.org/10.1155/2015/283145