The miR-17-92 cluster counteracts quiescence and chemoresistance in a distinct subpopulation of pancreatic cancer stem cells

OBJECTIVE: Cancer stem cells (CSCs) represent the root of many solid cancers including pancreatic ductal adenocarcinoma, are highly chemoresistant and represent the cellular source for disease relapse. However the mechanisms involved in these processes still need to be fully elucidated. Understandin...

Descripción completa

Detalles Bibliográficos
Autores principales: Cioffi, Michele, Trabulo, Sara M, Sanchez-Ripoll, Yolanda, Miranda-Lorenzo, Irene, Lonardo, Enza, Dorado, Jorge, Reis Vieira, Catarina, Ramirez, Juan Carlos, Hidalgo, Manuel, Aicher, Alexandra, Hahn, Stephan, Sainz, Bruno, Heeschen, Christopher
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2015
Materias:
Pancreas
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4680182/
https://www.ncbi.nlm.nih.gov/pubmed/25887381
http://dx.doi.org/10.1136/gutjnl-2014-308470

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4680182/
https://www.ncbi.nlm.nih.gov/pubmed/25887381
http://dx.doi.org/10.1136/gutjnl-2014-308470

Ejemplares similares