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The miR-17-92 cluster counteracts quiescence and chemoresistance in a distinct subpopulation of pancreatic cancer stem cells
OBJECTIVE: Cancer stem cells (CSCs) represent the root of many solid cancers including pancreatic ductal adenocarcinoma, are highly chemoresistant and represent the cellular source for disease relapse. However the mechanisms involved in these processes still need to be fully elucidated. Understandin...
Autores principales: | Cioffi, Michele, Trabulo, Sara M, Sanchez-Ripoll, Yolanda, Miranda-Lorenzo, Irene, Lonardo, Enza, Dorado, Jorge, Reis Vieira, Catarina, Ramirez, Juan Carlos, Hidalgo, Manuel, Aicher, Alexandra, Hahn, Stephan, Sainz, Bruno, Heeschen, Christopher |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BMJ Publishing Group
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4680182/ https://www.ncbi.nlm.nih.gov/pubmed/25887381 http://dx.doi.org/10.1136/gutjnl-2014-308470 |
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