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Evolution of lineage-specific functions in ancient cis-regulatory modules

Morphological evolution is driven both by coding sequence variation and by changes in regulatory sequences. However, how cis-regulatory modules (CRMs) evolve to generate entirely novel expression domains is largely unknown. Here, we reconstruct the evolutionary history of a lens enhancer located wit...

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Detalles Bibliográficos
Autores principales: Pauls, Stefan, Goode, Debbie K., Petrone, Libero, Oliveri, Paola, Elgar, Greg
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4680567/
https://www.ncbi.nlm.nih.gov/pubmed/26538567
http://dx.doi.org/10.1098/rsob.150079