Rat and human STINGs profile similarly towards anticancer/antiviral compounds

Cyclic dinucleotides (CDNs) and antitumor/antiviral agents (DMXAA and CMA) trigger STING-dependent innate immunity activation. Accumulative evidences have showed that DMXAA and CMA selectively activate mouse, but not human STING signaling. The mechanism underlying this species selectivity remains po...

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Detalles Bibliográficos
Autores principales: Zhang, Heng, Han, Min-Jie, Tao, Jianli, Ye, Zhao-Yang, Du, Xiao-Xia, Deng, Ming-Jing, Zhang, Xiao-Yan, Li, Lan-Fen, Jiang, Zheng-Fan, Su, Xiao-Dong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4680857/
https://www.ncbi.nlm.nih.gov/pubmed/26669264
http://dx.doi.org/10.1038/srep18035

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4680857/
https://www.ncbi.nlm.nih.gov/pubmed/26669264
http://dx.doi.org/10.1038/srep18035

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