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TATA boxes in gene transcription and poly (A) tails in mRNA stability: New perspective on the effects of berberine

Berberine (BBR) is a natural compound with variable pharmacological effects and a broad panel of target genes. We investigated berberine’s pharmacological activities from the perspective of its nucleotide-binding ability and discovered that BBR directly regulates gene expression by targeting TATA bo...

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Detalles Bibliográficos
Autores principales: Yuan, Zhi-Yi, Lu, Xi, Lei, Fan, Chai, Yu-Shuang, Wang, Yu-Gang, Jiang, Jing-Fei, Feng, Tian-Shi, Wang, Xin-Pei, Yu, Xuan, Yan, Xiao-Jin, Xing, Dong-Ming, Du, Li-Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4680869/
https://www.ncbi.nlm.nih.gov/pubmed/26671652
http://dx.doi.org/10.1038/srep18326