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TATA boxes in gene transcription and poly (A) tails in mRNA stability: New perspective on the effects of berberine
Berberine (BBR) is a natural compound with variable pharmacological effects and a broad panel of target genes. We investigated berberine’s pharmacological activities from the perspective of its nucleotide-binding ability and discovered that BBR directly regulates gene expression by targeting TATA bo...
Autores principales: | , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4680869/ https://www.ncbi.nlm.nih.gov/pubmed/26671652 http://dx.doi.org/10.1038/srep18326 |