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Twenty amino acids at the C-terminus of PA-X are associated with increased influenza A virus replication and pathogenicity

The PA-X protein, arising from ribosomal frameshift during PA translation, was recently discovered in influenza A virus (IAV). The C-terminal domain ‘X’ of PA-X proteins in IAVs can be classified as full-length (61 aa) or truncated (41 aa). In the main, avian influenza viruses express full-length PA...

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Detalles Bibliográficos
Autores principales: Gao, Huijie, Sun, Honglei, Hu, Jiao, Qi, Lu, Wang, Jinliang, Xiong, Xin, Wang, Yu, He, Qiming, Lin, Yang, Kong, Weili, Seng, Lai-Giea, Pu, Juan, Chang, Kin-Chow, Liu, Xiufan, Liu, Jinhua, Sun, Yipeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Society for General Microbiology 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4681059/
https://www.ncbi.nlm.nih.gov/pubmed/25877935
http://dx.doi.org/10.1099/vir.0.000143