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Evaluation of artemether-lumefantrine efficacy in the treatment of uncomplicated malaria and its association with pfmdr1, pfatpase6 and K13-propeller polymorphisms in Luanda, Angola

BACKGROUND: Drug resistance in Plasmodiumfalciparum has posed an obstacle to effective treatment and challenges many malaria control programmes in endemic areas. In Angola, until 2003, chloroquine (CQ) was used as first-line therapy for uncomplicated malaria. It was replaced initially by amodiaquine...

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Detalles Bibliográficos
Autores principales: Kiaco, Kinanga, Teixeira, Joana, Machado, Marta, do Rosário, Virgílio, Lopes, Dinora
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4681156/
https://www.ncbi.nlm.nih.gov/pubmed/26670642
http://dx.doi.org/10.1186/s12936-015-1018-3