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Electrophysiological analysis of mammalian cells expressing hERG using automated 384-well-patch-clamp
BACKGROUND: An in vitro electrophysiological assay system, which can assess compound effects and thus show cardiotoxicity including arrhythmia risks of test drugs, is an essential method in the field of drug development and toxicology. METHODS: In this study, high-throughput electrophysiological rec...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4681162/ https://www.ncbi.nlm.nih.gov/pubmed/26671227 http://dx.doi.org/10.1186/s40360-015-0042-9 |