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Electrophysiological analysis of mammalian cells expressing hERG using automated 384-well-patch-clamp

BACKGROUND: An in vitro electrophysiological assay system, which can assess compound effects and thus show cardiotoxicity including arrhythmia risks of test drugs, is an essential method in the field of drug development and toxicology. METHODS: In this study, high-throughput electrophysiological rec...

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Detalles Bibliográficos
Autores principales:	Haraguchi, Yuji, Ohtsuki, Atsushi, Oka, Takayuki, Shimizu, Tatsuya
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2015
Materias:	Technical Advance
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4681162/ https://www.ncbi.nlm.nih.gov/pubmed/26671227 http://dx.doi.org/10.1186/s40360-015-0042-9

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