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Eribulin in the Management of Advanced Breast Cancer: Implications of Current Research Findings
The search for cytotoxic agents from marine natural products ultimately led to the production of eribulin, which is a synthetic macrocyclic ketone analog of halichondrin B. Eribulin binds to tubulin to induce mitotic arrest and gained approval in Japan in May 2010; it was approved by the US Food and...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Libertas Academica
2015
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4681420/ https://www.ncbi.nlm.nih.gov/pubmed/26691012 http://dx.doi.org/10.4137/BCBCR.S32787 |