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Long-Lived αMUPA Mice Show Attenuation of Cardiac Aging and Leptin-Dependent Cardioprotection

αMUPA transgenic mice spontaneously consume less food compared with their wild type (WT) ancestors due to endogenously increased levels of the satiety hormone leptin. αMUPA mice share many benefits with mice under caloric restriction (CR) including an extended life span. To understand mechanisms lin...

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Detalles Bibliográficos
Autores principales: Levy, Esther, Kornowski, Ran, Gavrieli, Reut, Fratty, Ilana, Greenberg, Gabriel, Waldman, Maayan, Birk, Einat, Shainberg, Asher, Akirov, Amit, Miskin, Ruth, Hochhauser, Edith
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4681471/
https://www.ncbi.nlm.nih.gov/pubmed/26673217
http://dx.doi.org/10.1371/journal.pone.0144593