Antibodies to an interfering epitope in hepatitis C virus E2 can mask vaccine‐induced neutralizing activity

Hepatitis C virus (HCV) neutralization occurring at the E2 region 412‐426 (EP‐I) could be enhanced when antibodies directed specifically to the E2 region 434‐446 (EP‐II) were removed from serum samples of persistently infected patients and vaccinated chimpanzees, a phenomenon of so‐called antibody i...

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Detalles Bibliográficos
Autores principales: Kachko, Alla, Frey, Sharon E., Sirota, Lev, Ray, Ranjit, Wells, Frances, Zubkova, Iryna, Zhang, Pei, Major, Marian E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2015
Materias:
Viral Hepatitis
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4681649/
https://www.ncbi.nlm.nih.gov/pubmed/26251214
http://dx.doi.org/10.1002/hep.28108

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4681649/
https://www.ncbi.nlm.nih.gov/pubmed/26251214
http://dx.doi.org/10.1002/hep.28108

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