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Regulation of Mutant p53 Protein Expression

For several decades, p53 has been detected in cancer biopsies by virtue of its high protein expression level which is considered indicative of mutation. Surprisingly, however, mouse genetic studies revealed that mutant p53 is inherently labile, similar to its wild type (wt) counterpart. Consistently...

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Detalles Bibliográficos
Autores principales: Vijayakumaran, Reshma, Tan, Kah Hin, Miranda, Panimaya Jeffreena, Haupt, Sue, Haupt, Ygal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4681805/
https://www.ncbi.nlm.nih.gov/pubmed/26734569
http://dx.doi.org/10.3389/fonc.2015.00284