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Single-Cell Cytokine Gene Expression in Peripheral Blood Cells Correlates with Latent Tuberculosis Status

RNA flow cytometry (FISH-Flow) achieves high-throughput measurement of single-cell gene expression by combining in-situ nucleic acid hybridization with flow cytometry. We tested whether antigen-specific T-cell responses detected by FISH-Flow correlated with latent tuberculosis infection (LTBI), a co...

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Detalles Bibliográficos
Autores principales: Vir, Pooja, Arrigucci, Riccardo, Lakehal, Karim, Davidow, Amy L., Pine, Richard, Tyagi, Sanjay, Bushkin, Yuri, Lardizabal, Alfred, Gennaro, Maria Laura
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4681842/
https://www.ncbi.nlm.nih.gov/pubmed/26658491
http://dx.doi.org/10.1371/journal.pone.0144904