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Improved large-scale prediction of growth inhibition patterns using the NCI60 cancer cell line panel

Motivation: Recent large-scale omics initiatives have catalogued the somatic alterations of cancer cell line panels along with their pharmacological response to hundreds of compounds. In this study, we have explored these data to advance computational approaches that enable more effective and target...

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Detalles Bibliográficos
Autores principales: Cortés-Ciriano, Isidro, van Westen, Gerard J. P., Bouvier, Guillaume, Nilges, Michael, Overington, John P., Bender, Andreas, Malliavin, Thérèse E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4681992/
https://www.ncbi.nlm.nih.gov/pubmed/26351271
http://dx.doi.org/10.1093/bioinformatics/btv529