CLAMMS: a scalable algorithm for calling common and rare copy number variants from exome sequencing data

Motivation: Several algorithms exist for detecting copy number variants (CNVs) from human exome sequencing read depth, but previous tools have not been well suited for large population studies on the order of tens or hundreds of thousands of exomes. Their limitations include being difficult to integ...

Descripción completa

Detalles Bibliográficos
Autores principales: Packer, Jonathan S., Maxwell, Evan K., O’Dushlaine, Colm, Lopez, Alexander E., Dewey, Frederick E., Chernomorsky, Rostislav, Baras, Aris, Overton, John D., Habegger, Lukas, Reid, Jeffrey G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2016
Materias:
Applications Notes
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4681995/
https://www.ncbi.nlm.nih.gov/pubmed/26382196
http://dx.doi.org/10.1093/bioinformatics/btv547

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4681995/
https://www.ncbi.nlm.nih.gov/pubmed/26382196
http://dx.doi.org/10.1093/bioinformatics/btv547

Ejemplares similares