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A CDC42EP4/septin-based perisynaptic glial scaffold facilitates glutamate clearance

The small GTPase-effector proteins CDC42EP1-5/BORG1–5 interact reciprocally with CDC42 or the septin cytoskeleton. Here we show that, in the cerebellum, CDC42EP4 is exclusively expressed in Bergmann glia and localizes beneath specific membrane domains enwrapping dendritic spines of Purkinje cells. C...

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Detalles Bibliográficos
Autores principales: Ageta-Ishihara, Natsumi, Yamazaki, Maya, Konno, Kohtarou, Nakayama, Hisako, Abe, Manabu, Hashimoto, Kenji, Nishioka, Tomoki, Kaibuchi, Kozo, Hattori, Satoko, Miyakawa, Tsuyoshi, Tanaka, Kohichi, Huda, Fathul, Hirai, Hirokazu, Hashimoto, Kouichi, Watanabe, Masahiko, Sakimura, Kenji, Kinoshita, Makoto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4682051/
https://www.ncbi.nlm.nih.gov/pubmed/26657011
http://dx.doi.org/10.1038/ncomms10090